heartgard overdose

• 07-19-2006 8:08 PM

  luvmykids Joined on 06-21-2006 Posts 5 Points 0	heartgard overdose Reply Contact I was giving my dogs Heartgard and dropped one for dogs up to 25 pounds.  The dog that already got his dosage ate the one that dropped on the floor.  He normally gets 2 and he ate 3.  Should I worry or is this not enough to hurt him.  He is approxiamtely 50 pounds.   Thanks for any insight!
  	Post Points: 0

• 07-19-2006 9:23 PM

  In reply to luvmykids

  luvmykids Joined on 06-21-2006 Posts 5 Points 0	RE: heartgard overdose Reply Contact Just in case someone else does this... I just got advise from a vet assistant.  She said that he would have had to had more than that to be hurt.
  	Post Points: 0

• 07-19-2006 10:37 PM

  In reply to luvmykids

  dyan Joined on 09-10-2007 Ohio Posts 5,634 Points 105	RE: heartgard overdose Reply Contact I hope the vet assistant is correct...and probably is. However, I would be watching my dog for any adverse reactions. Dyan and Gibson
  	Post Points: 0

• 07-20-2006 2:16 AM

  In reply to luvmykids

  sandra_slayton Joined on 09-10-2007 Ingleside, Texas Posts 3,390 Points 0	RE: heartgard overdose Reply Contact I have been told by my vet they could actually eat 2 or 3 and be just fine.
  	Post Points: 0

• 07-20-2006 7:54 AM

  In reply to luvmykids

  calliecritturs Joined on 09-10-2007 Central Florida Posts 10,876 Points 3,330

  RE: heartgard overdose Reply Contact The dose of ivermectin in the HeartGuard tablets is absolutely minimal -- if you were treating the same dog for other kinds of mites it would be several times that amount (and the amount they use on demodectic mange is literally 100 times or more the dose for microfilaria/heartworm prevention).    The biggest concern, which is honestly minimal, is the other stuff to bind it together and get it into the body  -- for a dog sensitive to beef it might be a problem.    For a herding dog it could be a problem (corgi, sheltie, collie, shepherd, etc.) IF it's a dog sensitive to ivermectin.

  Post Points: 0

• 07-20-2006 8:26 AM

  In reply to luvmykids

  angelamarie Joined on 09-10-2007 Posts 403 Points 0	RE: heartgard overdose Reply Contact Callie will know if I'm right on this one or not--in Heartguard Plus it's the ingredient that makes it the "Plus" that can be a potential problem?
  	Post Points: 0

• 07-20-2006 10:31 AM

  In reply to luvmykids

  brookcove Joined on 09-10-2007 Semora, North Carolina, USA Posts 5,632 Points 695

  RE: heartgard overdose Reply Contact Ivermectin is potentially toxic.   But it's also true that the dose in the monthly preventative is teeny-tiny compared to other applications.  By the way, [linkhttp://psych.ucsf.edu/K9BehavioralGenetics/pdf/Literature%20PDF/Geyer%202005%20JVetPharmTher%20canine%20MDR1.pdf]early studies[/link] seem to indicate that Border collies are statistically free of the MDR1 mutation which makes some collies sensitive to a number of pharmaceuticals, including ivermectin.  Studies have also been unable to find this mutation in the bearded collie, though the working samples have been small.  It's still wise to test before treating, if nothing else to expand our statistical exposure!  [] If you have any dog that is in the [linkhttp://www.vetmed.wsu.edu/depts-VCPL/#Breeds]MDR1 mutation suspect list,[/link] (also see [linkhttp://www.msnbc.msn.com/id/5518665]http://www.msnbc.msn.com/id/5518665[/link] ) or a mix, I'd urge you to get the [linkhttp://www.vetmed.wsu.edu/depts-VCPL/]DNA test[/link] done - it's only about $60 plus the postage - because there are other drugs besides ivermectin that are contraindicated (see below) for these dogs.  It's just a cheek swab that you can do in your own home, then mail to the lab. Common drugs that are no-nos for dogs with the MDR1 mutation: [font="arial, verdana, helvetica, sans-serif"]Ivermectin (antiparasitic agent) [font="arial, verdana, helvetica, sans-serif"]Loperamide (Imodium®; over-the-counter antidiarrheal agent) [font="arial, verdana, helvetica, sans-serif"]Doxorubicin (anticancer agent) [font="arial, verdana, helvetica, sans-serif"]Vincristine (anticancer agent) [font="arial, verdana, helvetica, sans-serif"]Vinblastine (anticancer agent) [font="arial, verdana, helvetica, sans-serif"]Cyclosporin (immunosuppressive agent) [font="arial, verdana, helvetica, sans-serif"]Digoxin (heart drug) [font="arial, verdana, helvetica, sans-serif"] Acepromazine (tranquilizer) [font="arial, verdana, helvetica, sans-serif"] Butorphanol (pain control) "Ace" and "bute" are prescribed a LOT in emergency situations - unlike Hartguard, you won't have time to say, "Oh wait, my dog is an Aussie mix and might be sensitive." Becca Shouse: Irena Farm, Semora, NC Cord, Ted, Gus, Zhi, Maggie, Lynn, Lu, Min and Tully - and Sam! Waiting: Bubo & Ben http://irenafarm.blogspot.com Facebook: http://www.facebook.com/irenafarm?ref=profile

  Post Points: 0

• 07-20-2006 6:36 PM

  In reply to luvmykids

  jennie_c_d Joined on 09-10-2007 Southeast Georgia Posts 11,083 Points 265	RE: heartgard overdose Reply Contact I'm so tempted to have that test run on Emma. She is very sensitive to both ivermectin, and ace. She hasn't had any of those other drugs. I guess it doesn't really matter, since we're soooo careful about using drugs for her, and we don't know where she came from (to contribute to genetic research).
  	Post Points: 0

• 07-20-2006 6:49 PM

  In reply to luvmykids

  brookcove Joined on 09-10-2007 Semora, North Carolina, USA Posts 5,632 Points 695

  RE: heartgard overdose Reply Contact Wow, I wonder whether she might be a sheltie/jack, or something.  If you found out she's got the MDR1 mutation, it would tell you first, exactly what to be careful of.  There will be lots more information on this mutation to come because there's a bunch of frantic research going on as this mutation has tons of potential to DNA trace a specific "family" of dogs.  Without a doubt, if Emma is symptomatic, she can contribute data, even with her unknown background. Second, it might give you another clue on her own breeding!  To my knowlege there have been no purebred JRTs noted with MDR1m - but it's not out of the question that she's got some sheltie or even collie or Aussie in there.  I know it doesn't really matter in the long run, but it's fun to think about sometimes.  [] Becca Shouse: Irena Farm, Semora, NC Cord, Ted, Gus, Zhi, Maggie, Lynn, Lu, Min and Tully - and Sam! Waiting: Bubo & Ben http://irenafarm.blogspot.com Facebook: http://www.facebook.com/irenafarm?ref=profile

  Post Points: 0

• 07-20-2006 11:35 PM

  In reply to luvmykids

  jennie_c_d Joined on 09-10-2007 Southeast Georgia Posts 11,083 Points 265

  RE: heartgard overdose Reply Contact The kid actually herds. I've often wondered if there wasn't something else in there, but there's no way to know. I have had *two* people in seperate places, at seperate times, insist that she was part ACD. Honestly? I seriously doubt it. She's too typically BYBJRT. That doesn't mean there's not something else in there, it just means I can't tell that there is. Of course, her vet offered the info that Jacks don't come "speckled". I had to tell her that that's called "ticking" and the breed standard allows for it. Of course, this is all me musing. Before DNA testing, she needs a thyroid test, another bile acid test, her six months is coming up on her bloodwork, etc etc.

  Post Points: 0